Browsed by
Category: Medications

Morphine

Morphine

(ĐTĐ) – Morphine (INN) (MS Contin, MSIR, Avinza, Kadian, Oramorph, Roxanol, Kapanol) is a potent opiate analgesic medication and is considered to be the prototypical opioid.   Morphine is the most abundant alkaloid found in opium, the dried sap (latex) derived from shallowly slicing the unripe seedpods of the opium, or common or edible, poppy, Papaver somniferum. Morphine was the first active principle purified from a plant source and is one of at least 50 alkaloids of several different types…

Read More Read More

Opiate

Opiate

(ĐTĐ) – In medicine, the term opiate describes any of the narcotic opioid alkaloids found as natural products in the opium poppy plant, as well as many semisynthetic chemical derivatives of such alkaloids. Overview   Harvesting the poppy pod. Opiates are so named because they are constituents or derivatives of constituents found in opium, which is processed from the latex sap of the opium poppy, Papaver somniferum. The major biologically active opiates found in opium are morphine, codeine, thebaine, and…

Read More Read More

Opioid

Opioid

(ĐTĐ) – An opioid is a chemical that works by binding to opioid receptors, which are found principally in the central nervous system and the gastrointestinal tract. The receptors in these organ systems mediate both the beneficial effects and the side effects of opioids.   The analgesic (painkiller) effects of opioids are due to decreased perception of pain, decreased reaction to pain as well as increased pain tolerance. The side effects of opioids include sedation, respiratory depression, and constipation. Opioids…

Read More Read More

COX-2 inhibitor

COX-2 inhibitor

(ĐTĐ) – COX-2 selective inhibitor is a form of Non-steroidal anti-inflammatory drug (NSAID) that directly targets COX-2, an enzyme responsible for inflammation and pain.   Selectivity for COX-2 reduces the risk of peptic ulceration, and is the main feature of celecoxib, rofecoxib and other members of this drug class. COX-2 selectivity does not seem to reduce other adverse effects of NSAIDs (most notably an increased risk of renal failure), and some results have shown an increase in the risk for…

Read More Read More

Non-steroidal anti-inflammatory drug

Non-steroidal anti-inflammatory drug

(ĐTĐ) – Nonsteroidal anti-inflammatory drugs, usually abbreviated to NSAIDs or NAIDs, are drugs with analgesic and antipyretic (fever-reducing) effects and which have, in higher doses, anti-inflammatory effects (reducing inflammation). The term "nonsteroidal" is used to distinguish these drugs from steroids, which (among a broad range of other effects) have a similar eicosanoid-depressing, anti-inflammatory action. As analgesics, NSAIDs are unusual in that they are non-narcotic. Tiếng Việt >> NSAIDs are sometimes also referred to as nonsteroidal anti-inflammatory agents/analgesics (NSAIAs) or nonsteroidal…

Read More Read More

Analgesic

Analgesic

An analgesic (also known as a painkiller) is any member of the group of drugs used to relieve pain (achieve analgesia). The word analgesic derives from Greek an- (“without”) and algos (“pain”). Analgesic drugs act in various ways on the peripheral and central nervous systems; they include paracetamol (para-acetylaminophenol, also known in the US as acetaminophen), the non-steroidal anti-inflammatory drugs (NSAIDs) such as the salicylates, and opioid drugs such as morphine and opium. They are distinct from anesthetics, which reversibly…

Read More Read More

The journey from pain relief to addiction

The journey from pain relief to addiction

(ĐTĐ) – New research reveals that Australians are consuming more prescription drugs than ever before. Among the most dangerous and addictive families of drugs are opioids, strong pain killers used for people with injuries and drug dependencies. Increasingly the drugs seem to be being abused, as Shevonne Hunt writes.   Simon Millington did not have a history of drug abuse when he was first prescribed pain killers. He was 18 when he was in a terrible car accident and was…

Read More Read More

Ask the Pharmacist: What Will Hydrocodone Rescheduling Mean for Pharmacies?

Ask the Pharmacist: What Will Hydrocodone Rescheduling Mean for Pharmacies?

(ĐTĐ) – On October 6th, all hydrocodone combination products will be reclassified in the U.S. as a Schedule II drugs under the Controlled Substances Act. For all of those involved in dealing with chronic pain — prescribers, pharmacists, and patients — the impact could be more than minimal.   For the Pharmacist and his/her staff at your local pharmacy, it means that these drugs now have to be kept in a locked safe and a perpetual inventory has to be…

Read More Read More

New Drugs May Help Prevent Migraines

New Drugs May Help Prevent Migraines

(ĐTĐ) – Two experimental drugs may help prevent migraines in people who suffer multiple attacks a month, according to preliminary findings from a pair of clinical trials.   The drugs, one given by IV and one by injection, are part of a new approach to preventing migraine headaches. They are "monoclonal antibodies" that target a tiny protein called the calcitonin gene-related peptide (CGRP) — which recent research has implicated in triggering migraine pain. In one study, patients saw a 66…

Read More Read More

Are Medication Overuse Headaches Associated With NSAIDs?

Are Medication Overuse Headaches Associated With NSAIDs?

(ĐTĐ) – Question: Are medication overuse headaches associated with use of nonsteroidal anti-inflammatory drugs?   Response from Jenny A. Van Amburgh, PharmD, CDE (Assistant Dean of Academic Affairs; Associate Clinical Professor, School of Pharmacy, Northeastern University; Director, Clinical Pharmacy Team Director, Residency Program, Harbor Health Services, Inc., Boston, Massachusetts): Medication overuse headache (MOH), previously called "rebound headache," is a secondary chronic daily headache associated with an overused therapeutic agent in a headache-prone patient.[1] MOH is a headache that is present…

Read More Read More